Structure of PDB 8cef Chain K

Receptor sequence
>8cefK (length=88) Species: 10090 (Mus musculus) [Search protein sequence]
LPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEI
TKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKY
3D structure
PDB8cef Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA.
ChainK
Resolution2.486 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K A98 R105 K129 Q132 R135 R155 G156 G157 R158 A25 R32 K56 Q59 R62 R82 G83 G84 R85
BS02 dna K G88 Y89 Y91 K100 K104 V149 R150 R153 V154 R155 G156 R158 Y161 G15 Y16 Y18 K27 K31 V76 R77 R80 V81 R82 G83 R85 Y88
BS03 ZN K C79 C82 C99 C6 C9 C26
BS04 ZN K C115 C121 C131 C134 C42 C48 C58 C61
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8cef, PDBe:8cef, PDBj:8cef
PDBsum8cef
PubMed37503845
UniProtO08580|ERR1_MOUSE Steroid hormone receptor ERR1 (Gene Name=Esrra)

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