Structure of PDB 7x3w Chain K

Receptor sequence
>7x3wK (length=504) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DLEGTTKRFEHLLSLSGLFKHFIESKADPKFRQVLDVLEENQFRESPAYV
NGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIE
KIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLL
GCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLRE
FTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEE
DQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYK
KILEKDESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAK
LQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTA
HEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQ
ADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQ
NRTS
3D structure
PDB7x3w ISW1-N1 nucleosome
ChainK
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000182 rDNA binding
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0031491 nucleosome binding
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006354 DNA-templated transcription elongation
GO:0006355 regulation of DNA-templated transcription
GO:0006363 termination of RNA polymerase I transcription
GO:0006369 termination of RNA polymerase II transcription
GO:0007062 sister chromatid cohesion
GO:0009408 response to heat
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046832 negative regulation of RNA export from nucleus
GO:1902275 regulation of chromatin organization
GO:1903895 negative regulation of IRE1-mediated unfolded protein response
Cellular Component
GO:0005634 nucleus
GO:0016587 Isw1 complex
GO:0030874 nucleolar chromatin
GO:0036436 Isw1a complex
GO:0036437 Isw1b complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7x3w, PDBe:7x3w, PDBj:7x3w
PDBsum7x3w
PubMed38177688
UniProtP38144|ISW1_YEAST ISWI chromatin-remodeling complex ATPase ISW1 (Gene Name=ISW1)

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