Structure of PDB 7uph Chain K

Receptor sequence

>7uphK (length=271) Species: 562 (Escherichia coli) [Search protein sequence]

AVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITT
RHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGER
RYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKG
GQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHM
LRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQ
TKGKKTRSNKRTDKFIVRRRS

3D structure

PDB

7uph Three-dimensional structure-guided evolution of a ribosome with tethered subunits.

Chain

Resolution

4.18 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	K	P10 G11 R12 R13 H14 K17 H24 K25 G26 K27 P28 K35 K38 S39 R47 I48 H52 H57 K58 A60 Y61 R62 F66 E81 Y82 R86 K96 D97 G98 E99 M145 K146 P147 K149 Q152 L153 A154 R155 S156 A157 G158 L175 R176 S177 E179 R181 A197 H199 M200 V203 L204 G205 K206 A207 G208 W212 R216 T218 V219 R220 G221 M224 N225 V227 G233 G234 E235 R237 H242 W247 G253 K255 R257 R261 T262 R269 R270	P10 G11 R12 R13 H14 K17 H24 K25 G26 K27 P28 K35 K38 S39 R47 I48 H52 H57 K58 A60 Y61 R62 F66 E81 Y82 R86 K96 D97 G98 E99 M145 K146 P147 K149 Q152 L153 A154 R155 S156 A157 G158 L175 R176 S177 E179 R181 A197 H199 M200 V203 L204 G205 K206 A207 G208 W212 R216 T218 V219 R220 G221 M224 N225 V227 G233 G234 E235 R237 H242 W247 G253 K255 R257 R261 T262 R269 R270

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016740	transferase activity
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0032297	negative regulation of DNA-templated DNA replication initiation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0022625	cytosolic large ribosomal subunit
GO:1990082	DnaA-L2 complex
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7uph, PDBe:7uph, PDBj:7uph
PDBsum	7uph
PubMed	35836020
UniProt	P60422\|RL2_ECOLI Large ribosomal subunit protein uL2 (Gene Name=rplB)

[Back to BioLiP]