Structure of PDB 7u46 Chain K

Receptor sequence
>7u46K (length=205) Species: 9606 (Homo sapiens) [Search protein sequence]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNS
FKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQ
TPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFK
QYNQT
3D structure
PDB7u46 CENP-N promotes the compaction of centromeric chromatin.
ChainK
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K R44 M167 R44 M160
BS02 dna K P17 K45 K148 M167 R169 R170 P17 K45 K141 M160 R162 R163
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly

View graph for
Biological Process
External links
PDB RCSB:7u46, PDBe:7u46, PDBj:7u46
PDBsum7u46
PubMed35422519
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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