Structure of PDB 7scy Chain K

Receptor sequence
>7scyK (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
DKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEV
EKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWG
3D structure
PDB7scy The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
ChainK
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K K405 T420 G421 T422 K425 K19 T34 G35 T36 K39
External links
PDB RCSB:7scy, PDBe:7scy, PDBj:7scy
PDBsum7scy
PubMed34919819
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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