Structure of PDB 7rm4 Chain K

Receptor sequence
>7rm4K (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB7rm4 T cell receptors employ diverse strategies to target a p53 cancer neoantigen.
ChainK
Resolution3.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide K M5 Y7 M45 E63 R65 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 T143 W147 V152 L156 Y159 W167 Y171 M5 Y7 M45 E63 R65 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 T143 W147 V152 L156 Y159 W167 Y171
External links
PDB RCSB:7rm4, PDBe:7rm4, PDBj:7rm4
PDBsum7rm4
PubMed35124005
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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