Structure of PDB 7qo5 Chain K

Receptor sequence
>7qo5K (length=394) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
NNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQE
EVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPS
MSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEI
REAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAF
IRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDA
QTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRL
DRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIA
AIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK
3D structure
PDB7qo5 Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
ChainK
Resolution6.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP K P215 G216 T217 G218 K219 T220 M221 N319 P181 G182 T183 G184 K185 T186 M187 N285
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0036402 proteasome-activating activity
GO:0042802 identical protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0070682 proteasome regulatory particle assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008540 proteasome regulatory particle, base subcomplex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qo5, PDBe:7qo5, PDBj:7qo5
PDBsum7qo5
PubMed35149681
UniProtP33298|PRS6B_YEAST 26S proteasome regulatory subunit 6B homolog (Gene Name=RPT3)

[Back to BioLiP]