Structure of PDB 7qo4 Chain K

Receptor sequence
>7qo4K (length=394) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
NNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQE
EVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPS
MSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEI
REAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAF
IRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDA
QTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRL
DRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIA
AIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK
3D structure
PDB7qo4 Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
ChainK
Resolution7.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP K G216 T220 M221 I356 G380 G182 T186 M187 I322 G346
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0036402 proteasome-activating activity
GO:0042802 identical protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0070682 proteasome regulatory particle assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008540 proteasome regulatory particle, base subcomplex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7qo4, PDBe:7qo4, PDBj:7qo4
PDBsum7qo4
PubMed
UniProtP33298|PRS6B_YEAST 26S proteasome regulatory subunit 6B homolog (Gene Name=RPT3)

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