Structure of PDB 7qe7 Chain K

Receptor sequence

>7qe7K (length=531) [Search protein sequence]

MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMEEPDW
EMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLT
SHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIP
ESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVH
IGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARR
YLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPM
LYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTA
EKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQA
LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGH
CIEMYIGCYDFDVHTMKTLKNIISPPWDFRE

3D structure

PDB

7qe7 High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1

Chain

Resolution

Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	K	Y242 Y243 F247 V270 E277 A339 H342 A345 Y373 L376 H406 E407 F413 W444 E445 P446 N449 N450 H453 R456 K457 N478 Y487 S490 L491 F495 F514 E524 M525	Y221 Y222 F226 V249 E256 A318 H321 A324 Y352 L355 H385 E386 F392 W423 E424 P425 N428 N429 H432 R435 K436 N457 Y466 S469 L470 F474 F493 E503 M504

External links

PDB	RCSB:7qe7, PDBe:7qe7, PDBj:7qe7
PDBsum	7qe7
PubMed

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