Structure of PDB 7m5c Chain K

Receptor sequence
>7m5cK (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEQVAQDTEEVFRSYVFYRHQQEQEADPEMVTLPTMGQVGRQLAIIGDD
INRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGF
GYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAAL
3D structure
PDB7m5c Structural basis of BAK activation in mitochondrial apoptosis initiation.
ChainK
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide K D84 I85 R88 Y89 E92 T95 M96 H99 I114 S117 L118 N124 G126 R127 F134 D50 I51 R54 Y55 E58 T61 M62 H65 I80 S83 L84 N90 G92 R93 F100
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:7m5c, PDBe:7m5c, PDBj:7m5c
PDBsum7m5c
PubMed35017502
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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