Structure of PDB 7amv Chain K

Receptor sequence

>7amvK (length=708) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]

RYIVSPQLVLQVGKGQEVERALYLTPYDYIDEKSPIYYFLRSHLNIQQPE
IVKRHILLTLRMTQLKGYLGNLLDIKDDIIIYSHKNNLEYSYVDNTIFNP
FVYTQKKTLLKNDSFLYNVYPGACDFLVIWVARACDTSIPEFGSYEDVDN
NIIKFETMLMEVFPQLDLDITVESKFNNIFRTNLKLTGLKKIIQRVQDLD
INYKSLLSRYDEHFINMTGNHFILNDEQLNLSIWDLDGTLALSSDGDTVM
INNVKLFTDLVSDIDTQMERIKGDITYKVHLATPINSRIKLDIETSFIFI
ETATNNILLSSDKKISIILAKNHISIKVKNHIPNIEKYFTFLVIAINAMF
NSVQKSADFTKVETVYWSRICQNTKNKNRKPIIINYLDPGMKKISNNFYR
SDEKEVFINDNGIMFTCMDPLGKYNKVGFLNIFHDMRKYCIPCCFLHDQS
HRSTFSSCVHQIDVEKKIVSPYILNFGKVVTESKMSFLPIIFDAFLNDGM
TANMEQDNKRLKETSGYHIVRCCAGDDIVRLRTTSDIIQFVNEDKNILIV
NDMVYFPMNASDIGKKIHILIQEIVHEVMIVKKKESSDKIDFFPPNYKLL
KDLFPKQTIQTPIQSDAGMVLTTDGFYIDGKLFNEDLSSKYVTFTKNVIA
SDAVAKYFSPLFKYVISEAKDRFIKTWMINIMIHMNVDPNNIIPTLEKYY
PNSGRAQI

3D structure

PDB

7amv Structural basis of the complete poxvirus transcription initiation process.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	K	N307 I308 I319 A321 K322 H324 R370 I371 Q373 R380 Y425 I433 F446 K479 Q573	N306 I307 I318 A320 K321 H323 R369 I370 Q372 R379 Y424 I432 F445 K478 Q572
BS02	dna	K	T303 T305 I308 Y367 S369 K376 K381 H452 R453 Y473 L475 N476 K485 K510 R533	T302 T304 I307 Y366 S368 K375 K380 H451 R452 Y472 L474 N475 K484 K509 R532

Gene Ontology

	Biological Process
GO:0045893	positive regulation of DNA-templated transcription

View graph for
Biological Process

External links

PDB	RCSB:7amv, PDBe:7amv, PDBj:7amv
PDBsum	7amv
PubMed	34556871
UniProt	Q49QC6

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