Structure of PDB 6wwn Chain K

Receptor sequence
>6wwnK (length=361) Species: 10090 (Mus musculus) [Search protein sequence]
LGSNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFI
YDVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSG
KSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKI
HDLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELG
NKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLV
DLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIP
YRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIV
NIAKVNEDMNA
3D structure
PDB6wwn Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
ChainK
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AF3 K K488 S602 S603 A640 G641 K101 S215 S216 A253 G254
BS02 ADP K P402 T484 G485 G487 K488 S489 Y490 N599 S603 P15 T97 G98 G100 K101 S102 Y103 N212 S216
BS03 MG K S489 S603 S102 S216
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6wwn, PDBe:6wwn, PDBj:6wwn
PDBsum6wwn
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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