Structure of PDB 6wwk Chain K

Receptor sequence
>6wwkK (length=368) Species: 10090 (Mus musculus) [Search protein sequence]
LGSNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFI
YDVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSG
KSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKI
HDLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELG
NKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLV
DLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIP
YRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIV
NIAKVNEDMNAKLIRELK
3D structure
PDB6wwk Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
ChainK
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AF3 K T484 K488 N599 S602 S603 A640 T97 K101 N212 S215 S216 A253
BS02 ADP K P402 G487 K488 S489 Y490 N599 S603 P15 G100 K101 S102 Y103 N212 S216
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6wwk, PDBe:6wwk, PDBj:6wwk
PDBsum6wwk
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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