Structure of PDB 6wwh Chain K

Receptor sequence
>6wwhK (length=366) Species: 10090 (Mus musculus) [Search protein sequence]
FNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYD
VSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKS
YTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIHD
LLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNK
QRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLVDL
AGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYR
ESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVNI
AKVNEDMNAKLIRELK
3D structure
PDB6wwh Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
ChainK
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG K S489 S603 S100 S214
BS02 ANP K R401 P402 S444 T484 G485 G487 K488 S489 Y490 S602 S603 R12 P13 S55 T95 G96 G98 K99 S100 Y101 S213 S214
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6wwh, PDBe:6wwh, PDBj:6wwh
PDBsum6wwh
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

[Back to BioLiP]