Structure of PDB 6wwg Chain K

Receptor sequence
>6wwgK (length=367) Species: 10090 (Mus musculus) [Search protein sequence]
EFNSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIY
DVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGK
SYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIH
DLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGN
KQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLVD
LAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPY
RESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVN
IAKVNEDMNAKLIRELK
3D structure
PDB6wwg Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
ChainK
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AF3 K S602 S603 A640 G641 S214 S215 A252 G253
BS02 ADP K R401 G485 G487 K488 S489 Y490 N599 R13 G97 G99 K100 S101 Y102 N211
BS03 MG K S489 S603 S101 S215
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6wwg, PDBe:6wwg, PDBj:6wwg
PDBsum6wwg
PubMed34131133
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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