Structure of PDB 6qem Chain K

Receptor sequence
>6qemK (length=239) Species: 562 (Escherichia coli) [Search protein sequence]
MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAALERENRA
MKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIA
SFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSG
TSEEQLLNDLSNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGM
LTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSR
3D structure
PDB6qem Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
ChainK
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K F146 Y179 F146 Y179
BS02 ADP K H66 Y74 R75 P108 G109 T110 G111 K112 N113 H114 Y236 R237 H66 Y74 R75 P108 G109 T110 G111 K112 N113 H114 Y236 R237
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0006271 DNA strand elongation involved in DNA replication
GO:0031297 replication fork processing
Cellular Component
GO:1990077 primosome complex
GO:1990100 DnaB-DnaC complex
GO:1990158 DnaB-DnaC-DnaT-PriA-PriB complex
GO:1990159 DnaB-DnaC-DnaT-PriA-PriC complex
GO:1990160 DnaB-DnaC-Rep-PriC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qem, PDBe:6qem, PDBj:6qem
PDBsum6qem
PubMed30797687
UniProtP0AEF0|DNAC_ECOLI Replicative helicase loader DnaC (Gene Name=dnaC)

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