Structure of PDB 6pwx Chain K

Receptor sequence
>6pwxK (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6pwx Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainK
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K Y41 R42 T45 R63 R72 R83 F84 Q85 R116 V117 T118 M120 Y5 R6 T9 R27 R36 R47 F48 Q49 R80 V81 T82 M84
BS02 dna K R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 P66 R69 R83 R4 Y5 P7 G8 V10 A11 R13 R27 K28 L29 P30 R33 R47
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6pwx, PDBe:6pwx, PDBj:6pwx
PDBsum6pwx
PubMed31804488
UniProtP84233|H32_XENLA Histone H3.2

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