Structure of PDB 6m0q Chain K

Receptor sequence
>6m0qK (length=504) Species: 915 (Nitrosomonas europaea) [Search protein sequence]
DISTVPDETYDALKLDRGKATPKETYEALVKRYKDPAHGAGKGTMGDYWE
PIAISIYMDPNTFYKPPVSPKEVAERKDCVECHSDETPVWVRAWKRSTHA
NLDKIRNLKSDDPLYYKKGKLEEVENNLRSMGKLGEKETLKEVGCIDCHV
DVNKKDKADHTKDIRMPTADTCGTCHLREFAERESERDTMVWPNGQWPAG
RPSHALDYTANIETTVWAAMPQREVAEGCTMCHTNQNKCDNCHTRHEFSA
AESRKPEACATCHSGVDHNNWEAYTMSKHGKLAEMNRDKWNWEVRLKDAF
SKGGQNAPTCAACHMEYEGEYTHNITRKTRWANYPFVPGIAENITSDWSE
ARLDSWVLTCTQCHSERFARSYLDLMDKGTLEGLAKYQEANAIVHKMYED
GTLTGQKTNRPNPPEPEKPGFGIFTQLFWSKGNNPASLELKVLEMAENNL
AKMHVGLAHVNPGGWTYTEGWGPMNRAYVEIQDEYTKMQELSALQARVNK
LEGK
3D structure
PDB6m0q Enhancement of the activity of hydroxylamine oxidoreductase by juglone, plant secondary metabolite.
ChainK
Resolution1.99 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H257 D291 H292 Y358 Y491
Catalytic site (residue number reindexed from 1) H233 D267 H268 Y334 Y467
Enzyme Commision number 1.7.2.6: hydroxylamine dehydrogenase.
1.7.2.9: hydroxylamine oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEC K W114 K262 D264 T268 R269 W90 K238 D240 T244 R245
BS02 ISW K W221 R225 A234 N235 T238 C253 C256 H257 C286 H287 H292 N357 F452 W197 R201 A210 N211 T214 C229 C232 H233 C262 H263 H268 N333 F428
BS03 HEC K S389 E390 R391 S365 E366 R367
BS04 HEC K H388 S389 H364 S365
BS05 ISW K G487 Y491 G463 Y467
BS06 HEC K Y140 K141 H200 E203 H228 N259 C263 C266 H267 S277 R278 R319 L320 M339 H347 Y116 K117 H176 E179 H204 N235 C239 C242 H243 S253 R254 R295 L296 M315 H323
BS07 HEC K T122 H123 K141 K144 V167 V176 C196 C199 H200 C263 H267 F272 S273 A274 T98 H99 K117 K120 V143 V152 C172 C175 H176 C239 H243 F248 S249 A250
BS08 HEC K Y81 Y88 P91 P94 E96 A98 C103 C106 H107 E110 C169 I170 H173 H184 I188 M190 Y57 Y64 P67 P70 E72 A74 C79 C82 H83 E86 C145 I146 H149 H160 I164 M166
BS09 HEC K Y81 H107 W114 W118 H123 V167 G168 C169 C172 H173 M190 P191 K262 D264 R269 H270 F272 Y57 H83 W90 W94 H99 V143 G144 C145 C148 H149 M166 P167 K238 D240 R245 H246 F248
BS10 HEC K H287 N294 Y298 H303 P332 T333 C334 C337 H338 T353 R354 W355 W380 M400 A482 H483 H263 N270 Y274 H279 P308 T309 C310 C313 H314 T329 R330 W331 W356 M376 A458 H459
BS11 HEC K P226 S227 H228 D231 A234 C256 H257 N259 N265 C266 C283 C286 H287 C334 I349 T353 A356 P202 S203 H204 D207 A210 C232 H233 N235 N241 C242 C259 C262 H263 C310 I325 T329 A332
BS12 HEC K H303 L306 F324 A331 P332 C384 C387 H388 F392 Y396 V484 H279 L282 F300 A307 P308 C360 C363 H364 F368 Y372 V460
External links
PDB RCSB:6m0q, PDBe:6m0q, PDBj:6m0q
PDBsum6m0q
PubMed38009977
UniProtQ50925|HAO_NITEU Hydroxylamine oxidoreductase (Gene Name=hao1)

[Back to BioLiP]