Structure of PDB 6gmx Chain K

Receptor sequence
>6gmxK (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
MMYVKLISSDGHEFIVKREHALTSGTIKAMLNEVNFREIPSHVLSKVCMY
FTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
3D structure
PDB6gmx Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
ChainK
Resolution2.533 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F7B K E64 P66 E102 M105 F109 E38 P40 E76 M79 F83 BindingDB: Kd=6.7nM
Gene Ontology
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process

View graph for
Biological Process
External links
PDB RCSB:6gmx, PDBe:6gmx, PDBj:6gmx
PDBsum6gmx
PubMed30040896
UniProtQ15369|ELOC_HUMAN Elongin-C (Gene Name=ELOC)

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