Structure of PDB 6fvy Chain K

Receptor sequence
>6fvyK (length=394) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQE
EVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPS
MSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEI
REAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAF
IRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDA
QTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRL
DRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIA
AIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK
3D structure
PDB6fvy Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
ChainK
Resolution6.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP K A172 D173 G176 L177 P215 G216 T217 G218 K219 T220 A138 D139 G142 L143 P181 G182 T183 G184 K185 T186
BS02 ATP K D304 R330 R333 D270 R296 R299
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0036402 proteasome-activating activity
GO:0042802 identical protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0070682 proteasome regulatory particle assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008540 proteasome regulatory particle, base subcomplex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fvy, PDBe:6fvy, PDBj:6fvy
PDBsum6fvy
PubMed30067984
UniProtP33298|PRS6B_YEAST 26S proteasome regulatory subunit 6B homolog (Gene Name=RPT3)

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