Structure of PDB 5yb0 Chain K

Receptor sequence
>5yb0K (length=316) Species: 5759 (Entamoeba histolytica) [Search protein sequence]
LEISHRSKEWINVMNETKALMKEVMDIPEGYEILFFGGGASLQFLMVAMN
LLNKKACYLDTGVWASKAIKEAENIGEVKIIGTSKDKNYTYIPEYQIPSD
YDYFHITTNNTIYGTEIRKDIESPIPLVADMSSDILSKPIDISKYSLIYA
GAQKNCGAAGVTIVIIKKEILGKVQRKIPIILDYQVHILNNSMYNTPPVI
SIFTVNQTLKYIKKIGGLKKIQELNEEKARLLYAEIDRNKIFRGTVRKKD
RSIMNVCFVMEEQYKQLENEFSEYALQKGIIGIKGHRSVGGFRASIYNAV
TIESVQALIKCMHDFE
3D structure
PDB5yb0 N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
ChainK
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP K G76 A77 S78 W101 T148 D167 S169 G39 A40 S41 W64 T111 D130 S132
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5yb0, PDBe:5yb0, PDBj:5yb0
PDBsum5yb0
PubMed30959130
UniProtQ60I38

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