Structure of PDB 5w1w Chain K

Receptor sequence
>5w1wK (length=272) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQGHTQDTELVETRPAGDGTFQKWAAVVVPSGEE
QRYTCHVQHEGLPEPVTLRWKP
3D structure
PDB5w1w A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
ChainK
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide K Y7 H9 R62 E63 S66 I73 N77 W97 H99 F116 W133 S143 K146 E152 Y159 W167 Y171 Y6 H8 R61 E62 S65 I72 N76 W96 H98 F115 W132 S142 K145 E151 Y158 W166 Y170
External links
PDB RCSB:5w1w, PDBe:5w1w, PDBj:5w1w
PDBsum5w1w
PubMed28972140
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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