Structure of PDB 5tvp Chain K

Receptor sequence
>5tvpK (length=249) Species: 10090 (Mus musculus) [Search protein sequence]
SSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAY
LKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLC
VNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFA
GDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAA
YKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVV
3D structure
PDB5tvp ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
ChainK
Resolution2.399 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K D132 E162 H236 S239 T240 D272 N274 R276 W307 L315 I317 Y321 H359 D12 E42 H116 S119 T120 D152 N154 R156 W187 L195 I197 Y201 H239
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5tvp, PDBe:5tvp, PDBj:5tvp
PDBsum5tvp
PubMed28912134
UniProtQ9JJX7|TYDP2_MOUSE Tyrosyl-DNA phosphodiesterase 2 (Gene Name=Tdp2)

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