Structure of PDB 5o5l Chain K

Receptor sequence
>5o5lK (length=224) Species: 1299331 (Mycobacterium intracellulare 1956) [Search protein sequence]
TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLF
ADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMV
VSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVA
GVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQE
RGRIEVKGKGVMRTWYLIGRKADE
3D structure
PDB5o5l Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation.
ChainK
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D256 I257 D300 R376 K411
Catalytic site (residue number reindexed from 1) D52 I53 D96 R172 K207
Enzyme Commision number 4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ONM K F260 T261 P269 S298 G299 D300 F56 T57 P65 S94 G95 D96
BS02 MN K S298 D300 S301 S94 D96 S97
Gene Ontology
Molecular Function
GO:0016849 phosphorus-oxygen lyase activity
Biological Process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:5o5l, PDBe:5o5l, PDBj:5o5l
PDBsum5o5l
PubMed29087332
UniProtX8CHM4

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