Structure of PDB 4ov5 Chain K

Receptor sequence
>4ov5K (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
GDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPSKTQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW
TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB4ov5 Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide.
ChainK
Resolution2.199 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide K L11 F13 Y47 D57 W61 L67 Q70 R71 T77 Y78 H81 N82 V85 L11 F13 Y47 D57 W61 L67 Q70 R71 T77 Y78 H81 N82 V85
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4ov5, PDBe:4ov5, PDBj:4ov5
PDBsum4ov5
PubMed25002586
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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