Structure of PDB 4iw3 Chain K

Receptor sequence
>4iw3K (length=378) Species: 160488 (Pseudomonas putida KT2440) [Search protein sequence]
LPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGKIDSAPEEKAGITINTAH
VEYNSTIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTR
EHILLSRQVGVPYIVVFLNKADLVAELLELVEMEVRDLLSTYDFPGDDTP
IIIGSARMALEGKDDNEMGTTAVKKLVETLDSYIPEPVRAIDQPFLMPIE
DVFSISGRGTVVTGRIERGIVRVQDPLEIVGLRDTTTTTCTGVEMFRKLL
DEGRAGENCGVLLRGTKRDDVERGQVLVKPGSVKPHTKFTAEVYVLSKEE
GGRHTPFFKGYRPQFYFRTTDVTGNCELPEGVEMVMPGDNIQMTVTLIKT
IAMEDGLRFAIREGGRTVGAGVVAKIIE
3D structure
PDB4iw3 Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
ChainK
Resolution2.697 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K25 T26 T62 H85
Catalytic site (residue number reindexed from 1) K16 T17 T45 H68
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP K D22 G24 K25 T26 T27 N136 K137 D139 S174 R176 D13 G15 K16 T17 T18 N119 K120 D122 S155 R157
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4iw3, PDBe:4iw3, PDBj:4iw3
PDBsum4iw3
PubMed25197067
UniProtQ88QP8|EFTU1_PSEPK Elongation factor Tu-A (Gene Name=tufA)

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