Structure of PDB 4hna Chain K

Receptor sequence
>4hnaK (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]
AESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQS
STSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEG
MGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLS
VHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRS
HSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNI
NKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSP
SSYNESETKSTLLFGQRAKTIKNTVSVNVELTA
3D structure
PDB4hna Structure of a kinesin-tubulin complex and implications for kinesin motility.
ChainK
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP K R14 R16 P17 S88 G90 K91 T92 H93 N198 R10 R12 P13 S84 G86 K87 T88 H89 N194
BS02 MG K T92 S202 T88 S198
BS03 ALF K T87 N198 S201 S202 A233 G234 T83 N194 S197 S198 A229 G230
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4hna, PDBe:4hna, PDBj:4hna
PDBsum4hna
PubMed23872990
UniProtP33176|KINH_HUMAN Kinesin-1 heavy chain (Gene Name=KIF5B)

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