Structure of PDB 4guo Chain K

Receptor sequence
>4guoK (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
HHEFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCP
IQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAP
ASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNS
SCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYR
E
3D structure
PDB4guo structure of p73 DNA binding domain complex with 12 bp DNA
ChainK
Resolution3.19 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna K S261 R293 A296 R300 S151 R183 A186 R190
BS02 dna K K138 R268 K28 R158
BS03 ZN K C194 H197 C258 C262 C84 H87 C148 C152
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4guo, PDBe:4guo, PDBj:4guo
PDBsum4guo
PubMed
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

[Back to BioLiP]