Structure of PDB 4gez Chain K

Receptor sequence
>4gezK (length=364) Species: 1129346 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/164/2009(H17N10))) [Search protein sequence]
WRAKSQMCEVKGWVPTHRGFPWGPELPGDLILSRRAYVSCDLTSCFKFFI
AYGLSANQHLLNTSMEWEESLYKTPIGSASTLSTSEMILPGRSSSACFDG
LKWTVLVANGRDRNSFIMIKYGEEVTDTFSASRGGPLRLPNSECICIEGS
CFVIVSDGPNVNQSVHRIYELQNGTVQRWKQLNTTGINFEYSTCYTINNL
IKCTGTNLWNDAKRPLLRFTKELNYQIVEPCNGAPTDFPRGGLTTPSCKM
AQEKGEGGIQGFILDEKPAWTSKTKAESSQNGFVLEQIPNGIESEGTVSL
SYELFSNKRTGRSGFFQPKGDLISGCQRICFWLEIEDQTVGLGMIQELST
FCGINSPVQNINWD
3D structure
PDB4gez Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site.
ChainK
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) W144 Y268 T283 Q357 R389
Catalytic site (residue number reindexed from 1) W67 Y191 T206 Q280 R312
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA K N284 D288 D314 G332 G334 N207 D211 D237 G255 G257
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gez, PDBe:4gez, PDBj:4gez
PDBsum4gez
PubMed23012478
UniProtH6QM85

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