Structure of PDB 4by9 Chain K

Receptor sequence
>4by9K (length=227) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MVEVKKHKFPGVYVVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRI
WNPHRSKLGAAIVNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGK
IYGIEFSPRVLRELVPIVEERRNIIPILGDATKPEEYRALVTKVDVIFED
VAQPTQAKILIDNAKAYLKRGGYGMIAVKSRSIDVTKEPEQVFKEVEREL
SEYFEVIERLNLEPYEKDHALFVVRKP
3D structure
PDB4by9 The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
ChainK
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna K H54 R109 Q153 P154 V185 H54 R109 Q153 P154 V185
BS02 rna K V35 Y36 G37 R55 K57 A83 S84 G85 T86 T87 V151 K179 R181 H219 V35 Y36 G37 R55 K57 A83 S84 G85 T86 T87 V151 K179 R181 H219
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0016740 transferase activity
GO:1990259 histone H2AQ104 methyltransferase activity
Biological Process
GO:0000494 box C/D sno(s)RNA 3'-end processing
GO:0006338 chromatin remodeling
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
Cellular Component
GO:0031428 box C/D methylation guide snoRNP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4by9, PDBe:4by9, PDBj:4by9
PDBsum4by9
PubMed24121435
UniProtQ8U4M2|FLPA_PYRFU Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase (Gene Name=flpA)

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