Structure of PDB 3uk6 Chain K

Receptor sequence
>3uk6K (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
GAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKAGRAV
LIAGQTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQFRRS
IGVRIKVSLHEIDVINSREIVREQINAKVAEWREEPGVLFIDEVHMLDIE
SFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIV
STTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLIT
AASLVCRKRKQVDDIKRVYSLFLDESRSTQYMK
3D structure
PDB3uk6 Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases.
ChainK
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP K A24 H25 H27 M46 V47 T81 G82 K83 T84 A85 Y362 I403 A2 H3 H5 M24 V25 T56 G57 K58 T59 A60 Y205 I246
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:3uk6, PDBe:3uk6, PDBj:3uk6
PDBsum3uk6
PubMed22748767
UniProtQ9Y230|RUVB2_HUMAN RuvB-like 2 (Gene Name=RUVBL2)

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