Structure of PDB 3j8y Chain K

Receptor sequence
>3j8yK (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
AESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQS
STSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEG
MGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLS
VHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRS
HSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNI
NKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSP
SSYNESETKSTLLFGQRAKTIKNTVSVNVE
3D structure
PDB3j8y High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation.
ChainK
Resolution5.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP K R14 R16 P17 T87 S88 G90 K91 T92 H93 N198 S201 S202 R10 R12 P13 T83 S84 G86 K87 T88 H89 N194 S197 S198
BS02 MG K T92 S202 T88 S198
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:3j8y, PDBe:3j8y, PDBj:3j8y
PDBsum3j8y
PubMed25415053
UniProtP33176|KINH_HUMAN Kinesin-1 heavy chain (Gene Name=KIF5B)

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