Structure of PDB 2i2x Chain K

Receptor sequence
>2i2xK (length=459) Species: 2208 (Methanosarcina barkeri) [Search protein sequence]
AKRYTSMAYANADEMTFGVSKYPVKAGLDLEIGAGYTIPEINYAPRPEAG
ASKEKLIKEYERITTDVMERMVQVGFPAIILETEHVQQMSNNPSWGAEVA
HAQKTIMEKYHDEYGIKCALRHTIGDIRENREFLQLRGDKYSVFLEAFEQ
CAENGADLLSVESMGGKEVFDYAVLRNDIPGLLYSIGCLGSIDMELIWTD
ISKIAKKTGTISAGDTDCAQANTAMFIGGGLLNKNLAHTIAVIARAISAP
RSLVAYEAGAVGPGKDCGYENIIVKAITGMPMTMEGKTSTCAHSDVMGNL
VMQCCDCWSNESVEYHGEFGGTTVQCWSETLAYDCALMNTALETKNDKVL
RDLMMLSDRYRDPQAYMLAYDNAYRVGQSIVKDGDNIYLRAKNAAIECCN
IIEEGAAGKLELSRFETKALADAKAALEALPDDMDKFMDDCLTKYKSEVK
VFKPENYGF
3D structure
PDB2i2x Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex
ChainK
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.90: methanol--corrinoid protein Co-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN K H318 E320 H316 E318
BS02 ZN K E164 C220 C269 E162 C218 C267
BS03 B13 K K169 A221 T225 F228 K167 A219 T223 F226
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
GO:0047152 methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity
Biological Process
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2i2x, PDBe:2i2x, PDBj:2i2x
PDBsum2i2x
PubMed17142327
UniProtQ46EH3|MTAB_METBF Methanol--corrinoid protein co-methyltransferase (Gene Name=mtaB)

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