Structure of PDB 2hhh Chain K

Receptor sequence
>2hhhK (length=119) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYA
AQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVD
DTPVPHNGCRPKKKFRKAS
3D structure
PDB2hhh The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
ChainK
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna K R12 Y20 N26 N27 I29 T31 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 R85 V114 H116 N117 C119 R120 K122 K123 K124 R2 Y10 N16 N17 I19 T21 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 R75 V104 H106 N107 C109 R110 K112 K113 K114
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hhh, PDBe:2hhh, PDBj:2hhh
PDBsum2hhh
PubMed16998488
UniProtP80376|RS11_THET8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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