Structure of PDB 2gxa Chain K

Receptor sequence
>2gxaK (length=273) [Search protein sequence]
SLQTEKFDFGTMVQWAYDHKYAEESKIAYEYALAAGSDSNARAFLATNSQ
AKHVKDCATMVRHYLRAETQALSMPAYIKARCKLATGEGSWKSILTFFNY
QNIELITFINALKLWLKGIPKKNCLAFIGPPNTGKSMLCNSLIHFLGGSV
LSFANHKSHFWLASLADTRAALVDDATHACWRYFDTYLRNALDGYPVSID
RKHKAAVQIKAPPLLVTSNIDVQAEDRYLYLHSRVQTFRFEQPCTDESGE
QPFNITDADWKSFFVRLWGRLDL
3D structure
PDB2gxa Mechanism of DNA translocation in a replicative hexameric helicase.
ChainK
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna K F464 K506 H507 F160 K202 H203
BS02 ADP K P435 N436 T437 G438 K439 S440 P131 N132 T133 G134 K135 S136
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2gxa, PDBe:2gxa, PDBj:2gxa
PDBsum2gxa
PubMed16855583
UniProtP03116|VE1_BPV1 Replication protein E1 (Gene Name=E1)

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