Structure of PDB 2ak4 Chain K

Receptor sequence

>2ak4K (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP

3D structure

PDB

2ak4 T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

Chain

Resolution

2.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	K	Y7 N63 I66 F67 Y74 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 V152 Q155 R156 Y159 L163 W167 Y171	Y7 N63 I66 F67 Y74 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 V152 Q155 R156 Y159 L163 W167 Y171

External links

PDB	RCSB:2ak4, PDBe:2ak4, PDBj:2ak4
PDBsum	2ak4
PubMed	16186824
UniProt	P01889\|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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