Structure of PDB 8g3d Chain JM

Receptor sequence
>8g3dJM (length=432) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDDAFNTFFSETG
AGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGH
YTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERL
SVDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNE
AIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQT
NLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDP
RHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINY
QPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHW
YVGEGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB8g3d Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
ChainJM
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GTP JM Q11 G12 Q15 D98 N101 S140 G143 G144 T145 I171 N206 Y224 Q11 G12 Q15 D91 N94 S133 G136 G137 T138 I164 N199 Y217
BS02 MG JM Q11 E71 D98 Q11 E64 D91
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8g3d, PDBe:8g3d, PDBj:8g3d
PDBsum8g3d
PubMed37061538
UniProtP41351|TBA_TETTH Tubulin alpha chain

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