Structure of PDB 8x5d Chain J

Receptor sequence
>8x5dJ (length=235) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPG
TSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVF
RDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFA
FSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGT
RGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
3D structure
PDB8x5d Mycobacterium tuberculosis type III-A CRISPR/Cas system crRNA and its maturation have atypical features.
ChainJ
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J G23 T52 S53 K55 G56 R59 G89 D90 T91 M95 F125 N127 I129 L138 R139 Y195 T201 R202 G22 T51 S52 K54 G55 R58 G88 D89 T90 M94 F124 N126 I128 L137 R138 Y194 T200 R201
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8x5d, PDBe:8x5d, PDBj:8x5d
PDBsum8x5d
PubMed38218299
UniProtP9WJF9|CSM3_MYCTU CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

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