Structure of PDB 8r03 Chain J

Receptor sequence
>8r03J (length=180) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
IPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLY
INSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRF
ALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIE
KIQKDTDRDNFLTAEEAKEYGLIDEVMVPE
3D structure
PDB8r03 Structure of Staphylococcus aureus ClpP Bound to the Covalent Active Site Inhibitor Cystargolide A.
ChainJ
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VSZ J G68 G69 V71 S98 M99 P125 L126 H142 I143 T146 G55 G56 V58 S85 M86 P112 L113 H129 I130 T133
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0051117 ATPase binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Cellular Component
GO:0005737 cytoplasm
GO:0009368 endopeptidase Clp complex

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Cellular Component
External links
PDB RCSB:8r03, PDBe:8r03, PDBj:8r03
PDBsum8r03
PubMed38029352
UniProtQ2G036|CLPP_STAA8 ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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