Structure of PDB 8jfl Chain J

Receptor sequence
>8jflJ (length=1033) Species: 9606 (Homo sapiens) [Search protein sequence]
ETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGGDQKAKIQDSLYCAA
GAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQD
PRPTTCLHSVFNVHTGDELLSYEEYGHLQINAVSLYLLYLVEMISSGLQI
IYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLA
KAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNT
DAALLPCISYPAFALDDEVLFSQTLDKVVRKLKGKYGFKRFLRDGYRTSL
EDPNRCYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVQEYQDLL
TPVLHHTTEGYPVVPKYYYVPADFVEYEKNNPGSQKRFPSNCGRDGKLFL
WGQALYIIAKLLADELISPKDIDPVQRYVPLKDQRNVSMRFSNQGPLEND
LVVHVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYLQLG
INEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVF
LLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAALK
KGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEELPEFKSFEELEPGQ
QPDVNISEWKDKPTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEG
TVSDHIERVYRRAGSQKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQV
TLGAFGHEEEVISNPLSPRVIQNIIYYKCNTHDEREAVIQQELVIHIGWI
ISNNPELFSGMLKIRIGWIIHAMEYELQIRGGDKPALDLYQLSPSEVKQL
LLDILQPQQNGRCWLNRRQIDGSLNRTPTGFYDRVWQILERTPNGIIVAG
KHLPQQPTLSDMTMYEMNFSLLVEDTLGNIDQPQYRQIVVELLMVVSIVL
ERNPELEFQDKVDLDRLVKEAFNEFQKDQSRLKEIEKQDDMTSFYNTPPL
GKRGTCSYLTKAVMNLLLEGEVKPNNDDPCLIS
3D structure
PDB8jfl Architecture and activation of human muscle phosphorylase kinase
ChainJ
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAR J I1008 V1009 R1012 N1013 T1070 I948 V949 R952 N953 T1010
BS02 FAR J N1013 E1015 C1090 N953 E955 C1030
BS03 ADP J R211 Y213 R214 R555 P556 I578 S795 P798 R169 Y171 R172 R513 P514 I536 S735 P738
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0006091 generation of precursor metabolites and energy
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005964 phosphorylase kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jfl, PDBe:8jfl, PDBj:8jfl
PDBsum8jfl
PubMed38548794
UniProtQ93100|KPBB_HUMAN Phosphorylase b kinase regulatory subunit beta (Gene Name=PHKB)

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