Structure of PDB 8d3q Chain J

Receptor sequence
>8d3qJ (length=190) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
SNEEDRYLMLSGLQHFQFCKRQWALIHIEQQWKLTVRAMPIQSKNLQISG
ICDVVEFVQDSEGIELSGVSGSYKAFPVEYKRGKPKKGDEDIVQLVAQAM
CLEEMLVCRIDKGYLFYNEIKHRVEVPITDALRDKVVQMAKEMHHYYENR
HTPKVKTGPFCNNCSLQSICLPKLMNKRSVKRYIEGRLSE
3D structure
PDB8d3q PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
ChainJ
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna J M11 G79 I80 M9 G50 I51
BS02 SF4 J C21 Q24 C190 C193 C199 C19 Q22 C161 C164 C170
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:8d3q, PDBe:8d3q, PDBj:8d3q
PDBsum8d3q
PubMed36272411
UniProtA0A4Y7WTW2

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