Structure of PDB 8bc8 Chain J

Receptor sequence
>8bc8J (length=263) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMTQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILP
KNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTV
HLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWD
GEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYE
RVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHE
VHRPSHFLNFALL
3D structure
PDB8bc8 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
ChainJ
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QB6 J Y2091 T2219 P2220 Y34 T162 P163
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
Biological Process
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005681 spliceosomal complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bc8, PDBe:8bc8, PDBj:8bc8
PDBsum8bc8
PubMed36974964
UniProtQ6P2Q9|PRP8_HUMAN Pre-mRNA-processing-splicing factor 8 (Gene Name=PRPF8)

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