Structure of PDB 8b5l Chain J

Receptor sequence

>8b5lJ (length=170) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTV
RSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGF
GIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRI
SKEEAMRWFQQKYDGIILPG

3D structure

PDB

8b5l Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.

Chain

Resolution

2.86 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	J	K19 C21 N23 C25 S51 A53 R54 F60 N97 N98 T102 N104 G106 F107 G108 G127 D129 Y131 V133	K12 C14 N16 C18 S44 A46 R47 F53 N90 N91 T95 N97 G99 F100 G101 G120 D122 Y124 V126
BS02	rna	J	N10 M12 Q46 T47 V49 T73 R75 G138 D143 K144 K145 R146 C150 I151 G152 K154 H155	N3 M5 Q39 T40 V42 T66 R68 G131 D136 K137 K138 R139 C143 I144 G145 K147 H148

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8b5l, PDBe:8b5l, PDBj:8b5l
PDBsum	8b5l
PubMed	36867692
UniProt	G1TUB8\|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)

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