Structure of PDB 7y38 Chain J

Receptor sequence
>7y38J (length=466) Species: 371094 (Chikungunya virus strain S27-African prototype) [Search protein sequence]
PVYVDIDADSAFLKALQRAYPMFEVEPRQVTPNDAANARAFSHLAIKLIE
QEIDPDSTILDIGSAPARRMMSDRKYHCVCPMRSAEDPERLANYARKLAS
AAGKVLDRNISGKIGDLQAVMAVPDTETPTFCLHTDVSCRQRADVAIYQD
VYAVHAPTSLYHQAIKGVRLAYWVGFDTTPFMYNAMAGAYPSYSTNWADE
QVLKAKNIGLCSTDLTEGRRGKLSIMRGKKLEPCDRVLFSVGSTLYPESR
KLLKSWHLPSVFHLKGKLSFTCRCDTVVSCEGYVVKRITMSPGLYGKTTG
YAVTHHADGFLMCKTTDTVDGERVSFSVCTYVPATICDQMTGILATEVTP
EDAQKLLVGLNQRIVVNGRTQRNTNTMKNYMIPVVAQAFSKWAKECRKDM
EDEKLLGVRERTLWAFKKQKTHTVYKRPDTQSIQKVQAEFDSFVVPSLWS
SGLSIPLRTRIKWLLS
3D structure
PDB7y38 Molecular architecture of the Chikungunya virus replication complex.
ChainJ
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN J H79 C134 H77 C132
BS02 GTP J R41 D152 Y154 Y248 E250 R39 D150 Y152 Y246 E248
BS03 ATP J P83 S86 D138 P249 P81 S84 D136 P247
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008174 mRNA methyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0016556 mRNA modification

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Molecular Function
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Biological Process
External links
PDB RCSB:7y38, PDBe:7y38, PDBj:7y38
PDBsum7y38
PubMed36449616
UniProtQ8JUX6|POLN_CHIKS Polyprotein P1234

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