Structure of PDB 7wh5 Chain J

Receptor sequence
>7wh5J (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIPIVYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIH
MYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGM
RHSLPNSRIMIHQPIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDR
YMSPMEAQEFGILDKVLVHPP
3D structure
PDB7wh5 Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
ChainJ
Resolution2.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9DF J L79 E82 H116 W146 L13 E16 H50 W80
BS02 9DF J L104 F105 Q107 S108 Y138 L38 F39 Q41 S42 Y72
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7wh5, PDBe:7wh5, PDBj:7wh5
PDBsum7wh5
PubMed36376309
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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