Structure of PDB 7r7a Chain J

Receptor sequence

>7r7aJ (length=145) Species: 1247190 (Saccharomyces cerevisiae BY4741)

NNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELA
FYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEE
ASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSL

3D structure

• PDB: 7r7a Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
• Chain: J
• Resolution: 3.04 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	J	A305 R309 K312 G315 K316 Q319 N320 Q324 R326 Q327 R331	A110 R114 K117 G120 K121 Q124 N125 Q129 R131 Q132 R136

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0005515 protein binding
• GO:0042802 identical protein binding

Biological Process

• GO:0000280 nuclear division
• GO:0006364 rRNA processing
• GO:0042254 ribosome biogenesis
• GO:0042273 ribosomal large subunit biogenesis

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0030687 preribosome, large subunit precursor
• GO:0034399 nuclear periphery

External links

• PDB: RCSB:7r7a, PDBe:7r7a, PDBj:7r7a
• PDBsum: 7r7a
• PubMed: 36482249
• UniProt: P36049|EBP2_YEAST rRNA-processing protein EBP2 (Gene Name=EBP2)