Structure of PDB 6zp4 Chain J

Receptor sequence
>6zp4J (length=33) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
ELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
3D structure
PDB6zp4 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
ChainJ
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J N160 K164 H165 S167 G168 R171 R175 N13 K17 H18 S20 G21 R24 R28
External links
PDB RCSB:6zp4, PDBe:6zp4, PDBj:6zp4
PDBsum6zp4
PubMed32680882
UniProtP0DTD1|R1AB_SARS2 Replicase polyprotein 1ab (Gene Name=rep)

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