Structure of PDB 6zmw Chain J

Receptor sequence
>6zmwJ (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
VRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFE
IIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGF
IVLTTSAGIMDHEEARRKHTGGKILGFFF
3D structure
PDB6zmw Structure of a human 48Stranslational initiation complex.
ChainJ
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J V2 R3 M4 V6 A8 N16 R20 R28 S31 K32 R57 K71 V74 I75 S76 D80 Q82 T105 T106 S107 H120 G122 F130 V1 R2 M3 V5 A7 N15 R19 R27 S30 K31 R56 K70 V73 I74 S75 D79 Q81 T104 T105 S106 H119 G121 F129
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0008284 positive regulation of cell population proliferation
GO:0009615 response to virus
GO:0042274 ribosomal small subunit biogenesis
GO:0045787 positive regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zmw, PDBe:6zmw, PDBj:6zmw
PDBsum6zmw
PubMed32883864
UniProtP62244|RS15A_HUMAN Small ribosomal subunit protein uS8 (Gene Name=RPS15A)

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