Structure of PDB 6wvv Chain J

Receptor sequence
>6wvvJ (length=458) Species: 5855 (Plasmodium vivax) [Search protein sequence]
TTVPQVVSLDPTTIPIDYHTPIDDLSIEVKDILIVFLLNSQIKINTGKLG
TSKSLAYVGCGPANEETELEIRKVAYALVTLLHDSKHKKVSIIFEIKIEE
ALFRFFLEHLFYEYVTDERFKSADFIKNLSHIANADAYKGQIDKARVYFY
GTYYAAQLIAAPSNYCNPVSLSNAAVELAQKVNLECKILDVKELEELKMG
AYLSVGKGSMYPNKFIHLTYKGAKKIALIGKGITFDSGGYNLKAAPGSMI
DLMKFDMSGCAAVLGCAYCIGTIKPDNVEVHFLSAVCENMVSKNSYRPGD
IITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLY
SLGTSYAGVFGNNDQLINKILSSSKTSNEPVWWLPIINEYRSSLNSKYAD
LNNISSVKASSVVASLFLKEFIENTPWAHIDIAGVSWNFKARKPKGFGVR
LLTEFVLN
3D structure
PDB6wvv Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases.
ChainJ
Resolution2.33 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.11.1: leucyl aminopeptidase.
3.4.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN J K390 D395 D415 K231 D236 D256
BS02 ZN J D395 D475 E477 D236 D316 E318
Gene Ontology
Molecular Function
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019538 protein metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6wvv, PDBe:6wvv, PDBj:6wvv
PDBsum6wvv
PubMed33303633
UniProtA5K3U9|AMPL_PLAVS Leucine aminopeptidase (Gene Name=LAP)

[Back to BioLiP]