Structure of PDB 6mxx Chain J

Receptor sequence
>6mxxJ (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
MNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDI
LLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYK
RMAVILSLEQGNRLREQYGL
3D structure
PDB6mxx An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
ChainJ
Resolution2.298 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 K6P J W1495 D1521 M1584 W13 D39 M102 BindingDB: IC50=1.3e+4nM
External links
PDB RCSB:6mxx, PDBe:6mxx, PDBj:6mxx
PDBsum6mxx
PubMed37773238
UniProtQ12888|TP53B_HUMAN TP53-binding protein 1 (Gene Name=TP53BP1)

[Back to BioLiP]